NUDT9

Across TCGA cell cohorts, NUDT9 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,889 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUDT9-associated GO terms across cancer lineages are Regulation of protein K48-linked deubiquitination, Regulation of SREBP signaling pathway, and Positive regulation of ER to Golgi vesicle-mediated transport. Each is linked with NUDT9 in more than 9 cancer types. Because this analysis shows association rather than direction, both NUDT9-to-partner and partner-to-NUDT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein K48-linked deubiquitination grouped by NUDT9-low versus NUDT9-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT9→partner) and Y-score (partner→NUDT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Regulation of protein K48-linked deubiquitination →	-0.064	-1.051	<.001	<.001	3	10
OVARY	Regulation of SREBP signaling pathway →	+0.107	+0.874	<.001	.001	3	10
LARGE_INTESTINE	Positive regulation of ER to Golgi vesicle-mediated transport →	+0.088	+0.529	<.001	<.001	3	9
STOMACH	Negative regulation of chromosome condensation →	+0.148	+0.677	<.001	<.001	3	8
SKIN	Endosomal lumen acidification →	+0.123	+0.702	<.001	<.001	3	8
LARGE_INTESTINE	Vesicle budding from membrane →	+0.062	+0.577	.004	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,889 associations by consensus.

Regulation of protein K48-linked deubiquitination by NUDT9 expression — PANCREAS

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