NUDT5

Across TCGA cell cohorts, NUDT5 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,524 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUDT5-associated GO terms across cancer lineages are Pentose catabolic process, tRNA 5'-leader removal, and ATP generation from poly-ADP-D-ribose. Each is linked with NUDT5 in more than 18 cancer types. Because this analysis shows association rather than direction, both NUDT5-to-partner and partner-to-NUDT5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pentose catabolic process grouped by NUDT5-low versus NUDT5-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT5→partner) and Y-score (partner→NUDT5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Pentose catabolic process →	+0.235	+0.800	<.001	<.001	3	19
BONE	tRNA 5'-leader removal →	+0.119	+0.745	<.001	<.001	3	14
LIVER	ATP generation from poly-ADP-D-ribose →	+0.132	+0.681	<.001	.002	3	13
LUNG_NSCLC_LUSC	'de novo' cotranslational protein folding →	+0.176	+1.014	.005	.001	2	13
UPPER_AERODIGESTIVE_TRACT	DNA replication initiation →	+0.138	+0.849	<.001	<.001	3	12
CNS	Positive regulation of mitochondrial ATP synthesis coupled electron transport →	+0.088	+0.549	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,524 associations by consensus.

Pentose catabolic process by NUDT5 expression — BONE

Explore this box plot interactively →