NUDT4

Across TCGA patient cohorts, NUDT4 protein abundance is significantly associated with the RNA expression of many other genes, with 9,174 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUDT4-associated genes across cancer lineages are AXIN2, DEDD, and RNF43. Each is linked with NUDT4 in more than 3 cancer types. Because this analysis shows association rather than direction, both NUDT4-to-partner and partner-to-NUDT4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUDT4 versus AXIN2 in COAD, with a Pearson correlation of 0.47.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT4→partner) and Y-score (partner→NUDT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	AXIN2 →	+1.759	+0.606	<.001	<.001	3	4
LSCC	DEDD →	-0.325	-0.282	.001	.001	3	4
COAD	RNF43 →	+1.318	+0.562	<.001	<.001	3	3
UCEC	ACSS3 →	+1.466	+0.469	<.001	.002	3	3
UCEC	PROX1 →	+2.050	+0.510	<.001	<.001	3	3
BRCA	SYTL2 →	+1.517	+0.449	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,174 associations by consensus.

NUDT4 vs AXIN2 — COAD

Explore this scatter interactively →