NUDT4

Across TCGA patient cohorts, NUDT4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT4-associated genes across cancer lineages are Epithelial cells, lymphatic Endothelial cells, and mv Endothelial cells. Each is linked with NUDT4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT4-to-partner and partner-to-NUDT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epithelial cells grouped by NUDT4-low versus NUDT4-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT4→partner) and Y-score (partner→NUDT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Epithelial cells →	-0.108	-3.321	.004	.010	2	1
UCEC	lymphatic Endothelial cells →	-0.027	-3.268	.030	.011	1	1
UCEC	mv Endothelial cells →	-0.032	-3.311	.010	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Epithelial cells by NUDT4 expression — UCEC

Explore this box plot interactively →