NUDT4

Across TCGA cell cohorts, NUDT4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,998 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible NUDT4-associated GO terms across cancer lineages are Diadenosine polyphosphate metabolic process, Diadenosine pentaphosphate catabolic process, and Diadenosine hexaphosphate catabolic process. Each is linked with NUDT4 in more than 12 cancer types. Because this analysis shows association rather than direction, both NUDT4-to-partner and partner-to-NUDT4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Diadenosine polyphosphate metabolic process grouped by NUDT4-low versus NUDT4-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT4→partner) and Y-score (partner→NUDT4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Diadenosine polyphosphate metabolic process →	+0.229	+1.287	<.001	<.001	3	13
PANCREAS	Diadenosine pentaphosphate catabolic process →	+0.412	+1.605	.009	<.001	3	9
PANCREAS	Diadenosine hexaphosphate catabolic process →	+0.412	+1.605	.009	<.001	3	9
PANCREAS	Adenosine 5'-(hexahydrogen pentaphosphate) catabolic process →	+0.412	+1.605	.009	<.001	3	9
PANCREAS	Diphosphoinositol polyphosphate metabolic process →	+0.412	+1.605	.009	<.001	3	9
SOFT_TISSUE	Vesicle budding from membrane →	+0.090	+1.209	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,998 associations by consensus.

Diadenosine polyphosphate metabolic process by NUDT4 expression — LIVER

Explore this box plot interactively →