NUDT3

Across TCGA pan-cancer cohorts, NUDT3 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NUDT3 data layer compared with 25 for mass-spec protein.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NUDT3 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NUDT3 expression acts as an unfavorable survival marker, although some lineages such as LSCC and GBM show a favorable association.

LSCC, HNSC, and GBM are the cancer types where NUDT3 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Median	All	0.899	0.656	.002	17	view →
HNSC	OS	Quartile	II,III,IV	0.815	0.970	.008	8	view →
GBM	OS	Tertile	All	0.981	0.830	.009	5	view →
CCRCC	OS	Median	II,III,IV	0.454	1.000	.014	3	view →
LUAD	OS	Median	All	0.914	0.972	.030	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NUDT3–LSCC (OS)

Open the LSCC breakdown →