NUDT3

Across TCGA patient cohorts, NUDT3 protein abundance is significantly associated with the RNA expression of many other genes, with 12,907 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUDT3-associated genes across cancer lineages are TMEM170B, HCG15, and PTK6. Each is linked with NUDT3 in more than 5 cancer types. Because this analysis shows association rather than direction, both NUDT3-to-partner and partner-to-NUDT3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUDT3 versus TMEM170B in GBM, with a Pearson correlation of 0.43.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT3→partner) and Y-score (partner→NUDT3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TMEM170B →	+0.816	+0.421	<.001	<.001	3	6
OV	HCG15 →	+1.045	+0.414	<.001	<.001	3	5
HNSC	PTK6 →	-0.872	-0.223	<.001	<.001	3	4
HNSC	LSM2 →	+0.876	+0.368	.001	<.001	3	4
UCEC	TPI1 →	-1.444	-0.558	<.001	<.001	3	4
UCEC	SPAG4 →	-1.205	-0.564	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,907 associations by consensus.

NUDT3 vs TMEM170B — GBM

Explore this scatter interactively →