NUDT22

Across TCGA patient cohorts, NUDT22 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,151 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUDT22-associated GO terms across cancer lineages are Alditol biosynthetic process, GDP-mannose metabolic process, and Glyceraldehyde-3-phosphate metabolic process. Each is linked with NUDT22 in more than 22 cancer types. Because this analysis shows association rather than direction, both NUDT22-to-partner and partner-to-NUDT22 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Alditol biosynthetic process grouped by NUDT22-low versus NUDT22-high in PAAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT22→partner) and Y-score (partner→NUDT22) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PAAD	Alditol biosynthetic process →	+0.070	+0.521	<.001	<.001	3	23
SCLC	GDP-mannose metabolic process →	+0.099	+0.305	.005	.007	1	20
DLBC	Glyceraldehyde-3-phosphate metabolic process →	+0.092	+0.603	<.001	<.001	2	19
TGCT	L-proline biosynthetic process →	+0.057	+0.450	<.001	<.001	3	18
LAML	Regulation of cytochrome-c oxidase activity →	+0.039	+0.502	<.001	<.001	3	17
UVM	Protein insertion into ER membrane by stop-transfer membrane-anchor sequence →	+0.041	+0.543	<.001	<.001	2	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,151 associations by consensus.

Alditol biosynthetic process by NUDT22 expression — PAAD

Explore this box plot interactively →