NUDT21

Across TCGA cell cohorts, NUDT21 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,208 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUDT21-associated GO terms across cancer lineages are mRNA alternative polyadenylation, Protein localization to chromosome, and Centrosome duplication. Each is linked with NUDT21 in more than 18 cancer types. Because this analysis shows association rather than direction, both NUDT21-to-partner and partner-to-NUDT21 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, mRNA alternative polyadenylation grouped by NUDT21-low versus NUDT21-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT21→partner) and Y-score (partner→NUDT21) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	mRNA alternative polyadenylation →	+0.089	+0.964	<.001	<.001	3	19
SOFT_TISSUE	Protein localization to chromosome →	+0.080	+0.791	<.001	<.001	3	15
PANCREAS	Centrosome duplication →	+0.083	+0.876	.001	<.001	3	15
SOFT_TISSUE	Microtubule organizing center organization →	+0.073	+0.809	<.001	<.001	3	14
SOFT_TISSUE	RNA export from nucleus →	+0.142	+1.086	<.001	<.001	3	14
BREAST	mRNA export from nucleus →	+0.096	+0.940	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,208 associations by consensus.

mRNA alternative polyadenylation by NUDT21 expression — SKIN

Explore this box plot interactively →