NUDT2

Across TCGA cell cohorts, NUDT2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,888 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUDT2-associated GO terms across cancer lineages are AMP biosynthetic process, Purine nucleoside monophosphate biosynthetic process, and AMP metabolic process. Each is linked with NUDT2 in more than 14 cancer types. Because this analysis shows association rather than direction, both NUDT2-to-partner and partner-to-NUDT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMP biosynthetic process grouped by NUDT2-low versus NUDT2-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT2→partner) and Y-score (partner→NUDT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	AMP biosynthetic process →	+0.117	+0.845	<.001	<.001	3	15
URINARY_TRACT	Purine nucleoside monophosphate biosynthetic process →	+0.106	+1.051	.001	<.001	3	12
URINARY_TRACT	AMP metabolic process →	+0.121	+0.763	<.001	.001	3	10
LUNG_NSCLC_LUSC	Purine ribonucleoside monophosphate biosynthetic process →	+0.112	+1.503	.003	<.001	2	11
SKIN	Purine nucleoside monophosphate metabolic process →	+0.075	+0.839	<.001	<.001	3	8
LUNG_NSCLC_LUAD	Cell junction assembly →	-0.040	-0.515	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,888 associations by consensus.

AMP biosynthetic process by NUDT2 expression — URINARY_TRACT

Explore this box plot interactively →