Across TCGA patient cohorts, NUDT16 mutation is significantly associated with the RNA expression of many other genes, with 315 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT16-associated genes across cancer lineages are TUBB8P5, RPL23AP88, and DOC2B. Each is linked with NUDT16 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT16-to-partner and partner-to-NUDT16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT16→partner) and Y-score (partner→NUDT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TUBB8P5 →	+0.732	+2.552	<.001	.002	3	2
UCEC	RPL23AP88 →	+0.181	+2.332	.004	.005	3	1
UCEC	DOC2B →	-1.387	-3.459	<.001	.005	3	1
UCEC	ZNHIT3 →	+0.490	+3.345	.009	.005	3	1
UCEC	F8A2 →	+0.029	+3.109	<.001	.007	3	1
UCEC	RNVU1-28 →	+1.042	+2.635	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 315 associations by consensus.

Exploration

NUDT16 survival (RNA) · tumor vs normal (RNA) · all NUDT16 data types