Across TCGA patient cohorts, NUDT16 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT16-associated genes across cancer lineages are ACC_pS79, ACC1, and Ku80. Each is linked with NUDT16 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT16-to-partner and partner-to-NUDT16 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT16→partner) and Y-score (partner→NUDT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ACC_pS79 →	+0.586	+3.169	.002	.020	3	1
UCEC	ACC1 →	+0.719	+3.169	<.001	.020	3	1
UCEC	Ku80 →	+0.469	+3.183	<.001	.010	3	1
UCEC	p27_pT157 →	-0.092	-3.169	.003	.020	3	1
UCEC	Annexin-1 →	+0.733	+2.827	.011	.035	3	1
UCEC	Caspase-8 →	-0.275	-3.169	.046	.020	2	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

Exploration

NUDT16 survival (RNA) · tumor vs normal (RNA) · all NUDT16 data types