NUDT14

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NUDT14 mutation is significantly associated with the RNA expression of many other genes, with 190 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible NUDT14-associated genes across cancer lineages are RNU6-1246P, MIR3689B, and PRAMEF28P. Each is linked with NUDT14 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT14-to-partner and partner-to-NUDT14 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT14→partner) and Y-score (partner→NUDT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
COADRNU6-1246P →+1.377+7.741<.001.00932
COADMIR3689B →+0.273+7.741<.001.00932
CESCPRAMEF28P →+0.130+5.969<.001.00232
UCECTRBV17 →+0.321+3.086<.001.00732
SKCMPALLD-AS1 →+0.115+4.979.009.00932
BLCAMIR548AX →+0.552+6.618<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 190 associations by consensus.

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