NUDT13

Across TCGA patient cohorts, NUDT13 mutation is significantly associated with the total protein of many other genes, with 15 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT13-associated genes across cancer lineages are FoxM1, Heregulin, and JNK2. Each is linked with NUDT13 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT13-to-partner and partner-to-NUDT13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FoxM1 grouped by NUDT13-low versus NUDT13-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT13→partner) and Y-score (partner→NUDT13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FoxM1 →	+0.238	+2.000	.041	.032	3	1
UCEC	Heregulin →	-0.175	-2.321	.001	.034	3	1
UCEC	JNK2 →	+0.320	+2.331	<.001	.019	3	1
UCEC	p62 Lck ligand →	+0.366	+2.179	.012	.034	3	1
UCEC	P-Cadherin →	-0.160	-2.999	.013	.035	3	1
UCEC	Rab25 →	-0.398	-2.000	.007	.032	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 15 associations by consensus.

FoxM1 by NUDT13 expression — UCEC

Explore this box plot interactively →