NUDT12

Across TCGA patient cohorts, NUDT12 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,008 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NUDT12-associated proteins across cancer lineages are PLEKHA1_S177, PLEKHA6, and PLEKHA7_S903. Each is linked with NUDT12 in more than 4 cancer types. Because this analysis shows association rather than direction, both NUDT12-to-partner and partner-to-NUDT12 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUDT12 versus PLEKHA1_S177 in UCEC, with a Pearson correlation of 0.42.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT12→partner) and Y-score (partner→NUDT12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PLEKHA1_S177 →	+1.233	+0.727	.009	.002	3	4
LUAD	PLEKHA6 →	+0.415	+0.551	.004	<.001	3	4
UCEC	PLEKHA7_S903 →	+0.587	+0.752	.002	<.001	3	4
BRCA	SGSM3 →	+0.371	+0.876	<.001	<.001	3	4
GBM	ARPC5 →	-0.288	-0.371	<.001	.004	3	4
LSCC	ACTR2 →	-0.227	-0.515	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,008 associations by consensus.

NUDT12 vs PLEKHA1_S177 — UCEC

Explore this scatter interactively →