Across TCGA patient cohorts, NUDT11 mutation is significantly associated with the total protein of many other genes, with 35 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT11-associated genes across cancer lineages are FOXO3a_pS318_S321, JNK2, and C-Raf_pS338. Each is linked with NUDT11 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT11-to-partner and partner-to-NUDT11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT11→partner) and Y-score (partner→NUDT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FOXO3a_pS318_S321 →	-0.130	-1.584	.004	.032	3	2
UCEC	JNK2 →	+0.213	+3.196	.003	.009	3	2
UCEC	C-Raf_pS338 →	-0.103	-1.847	<.001	.008	3	2
UCEC	EGFR_pY1068 →	-0.263	-1.847	.004	.008	3	1
UCEC	EGFR →	-0.176	-3.321	.002	.010	3	1
UCEC	eIF4E →	+0.183	+1.750	.018	.049	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

Exploration

NUDT11 survival (RNA) · tumor vs normal (RNA) · all NUDT11 data types