Across TCGA cell cohorts, NUDT11 mutation is significantly associated with the mutation status of many other genes, with 279 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUDT11-associated genes across cancer lineages are ZNF175, CFAP52, and POTEF. Each is linked with NUDT11 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT11-to-partner and partner-to-NUDT11 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT11→partner) and Y-score (partner→NUDT11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	ZNF175 →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	CFAP52 →	+6.321	+6.321	.001	.001	1	2
BLOOD_Leukemia	POTEF →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	SLC39A10 →	+4.321	+5.285	.005	.005	1	2
LARGE_INTESTINE	PIGV →	+4.523	+5.087	.006	.006	1	2
LARGE_INTESTINE	MSX2 →	+5.523	+5.523	.003	.003	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 279 associations by consensus.

Exploration

NUDT11 survival (RNA) · tumor vs normal (RNA) · all NUDT11 data types