NUDT10

Across TCGA patient cohorts, NUDT10 mutation is significantly associated with the RNA expression of many other genes, with 2,403 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUDT10-associated genes across cancer lineages are RNA5SP411, PRAMEF25, and MIR3118-3. Each is linked with NUDT10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT10-to-partner and partner-to-NUDT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP411 grouped by NUDT10-low versus NUDT10-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT10→partner) and Y-score (partner→NUDT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP411 →	+1.103	+1.808	<.001	.007	3	2
SKCM	PRAMEF25 →	+0.019	+6.219	<.001	<.001	3	2
BRCA	MIR3118-3 →	+0.558	+8.471	<.001	.005	3	1
UCEC	SRXN1 →	+0.514	+2.137	.001	.009	3	1
UCEC	MAP3K4-AS1 →	+0.865	+3.169	<.001	<.001	3	1
UCEC	DCP1A →	+0.605	+2.502	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,403 associations by consensus.

RNA5SP411 by NUDT10 expression — UCEC

Explore this box plot interactively →