NUDT10

Across TCGA cell cohorts, NUDT10 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUDT10-associated genes across cancer lineages are ITGAD and TEX43. Each is linked with NUDT10 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDT10-to-partner and partner-to-NUDT10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ITGAD grouped by NUDT10-low versus NUDT10-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT10→partner) and Y-score (partner→NUDT10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ITGAD →	+0.015	+4.095	<.001	.009	3	1
BLOOD_Leukemia	TEX43 →	+0.098	+4.969	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

ITGAD by NUDT10 expression — LARGE_INTESTINE

Explore this box plot interactively →