NUDT1

Across TCGA cell cohorts, NUDT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,412 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NUDT1-associated GO terms across cancer lineages are Spindle elongation, Meiotic cell cycle, and Double-strand break repair via break-induced replication. Each is linked with NUDT1 in more than 15 cancer types. Because this analysis shows association rather than direction, both NUDT1-to-partner and partner-to-NUDT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Spindle elongation grouped by NUDT1-low versus NUDT1-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDT1→partner) and Y-score (partner→NUDT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Spindle elongation →	+0.254	+1.431	.001	.002	3	16
PANCREAS	Meiotic cell cycle →	+0.077	+0.856	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Double-strand break repair via break-induced replication →	+0.270	+1.519	<.001	<.001	3	16
BONE	DNA replication initiation →	+0.174	+0.960	.001	.001	3	16
OESOPHAGUS	Attachment of spindle microtubules to kinetochore →	+0.104	+0.610	.003	.003	3	15
BLOOD_Myeloma	Positive regulation of mitotic sister chromatid separation →	+0.166	+1.479	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,412 associations by consensus.

Spindle elongation by NUDT1 expression — BLOOD_Myeloma

Explore this box plot interactively →