NUDCP2

Across TCGA pan-cancer cohorts, NUDCP2 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of NUDCP2’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where NUDCP2 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NUDCP2 is over-expressed in tumor, although a few such as THCA and KICH show the opposite, repressed pattern.

COAD, THCA, and HNSC are the cancer types where NUDCP2 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NUDCP2 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Female	II,III,IV	+0.781	<.001	7	view →
THCA	All	All	−0.220	<.001	7	view →
HNSC	Male	All	+0.257	<.001	6	view →
LIHC	All	II,III,IV	+0.216	<.001	6	view →
KIRP	All	IV	+0.492	.011	5	view →
CHOL	All	All	+0.797	<.001	4	view →
LUSC	All	All	+0.173	.009	4	view →
BLCA	Female	All	+0.350	.011	3	view →
LUAD	All	III,IV	+0.271	.011	2	view →
KICH	All	All	−0.188	.010	2	view →
READ	All	II,III,IV	+0.520	.035	1	view →
STAD	All	II,III,IV	+0.205	.046	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

NUDCP2–COAD

Open the COAD breakdown →