Across TCGA pan-cancer cohorts, NUDCP1 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of NUDCP1’s most consistent transcriptional readouts.
The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NUDCP1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NUDCP1 is over-expressed in tumor, although a few such as PAAD show the opposite, repressed pattern.
HNSC, KIRC, and COAD are the cancer types where NUDCP1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NUDCP1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.