NUDCD3

Across TCGA cell cohorts, NUDCD3 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUDCD3-associated genes across cancer lineages are PRR23C, P2RY12, and CD300H. Each is linked with NUDCD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDCD3-to-partner and partner-to-NUDCD3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRR23C grouped by NUDCD3-low versus NUDCD3-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDCD3→partner) and Y-score (partner→NUDCD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PRR23C →	+0.006	+4.736	<.001	.009	3	1
LARGE_INTESTINE	P2RY12 →	+0.236	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CD300H →	+0.039	+4.415	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

PRR23C by NUDCD3 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →