NUDCD1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NUDCD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NUDCD1 data layer compared with 22 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NUDCD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NUDCD1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.

CCRCC, HNSC, and LSCC are the cancer types where NUDCD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CCRCCOSMedianII,III,IV0.6030.872.00515view →
HNSCOSQuartileAll0.7830.964.0078view →
LSCCDFSMedianII,III,IV0.8130.564.0363view →
PDACOSMedianAll0.7150.909.0243view →
LUADDFSMedianAll0.5050.899.0152view →
Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NUDCD1–CCRCC (OS)

Kaplan–Meier survival curve for NUDCD1 mass-spec protein-high vs -low samples in CCRCC.

Open the CCRCC breakdown →

Exploration