Across TCGA pan-cancer cohorts, NUDCD1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NUDCD1 data layer compared with 22 for mass-spec protein and 2 for mutation status.
The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NUDCD1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NUDCD1 expression acts as an unfavorable survival marker, although some lineages such as LSCC show a favorable association.
CCRCC, HNSC, and LSCC are the cancer types where NUDCD1 mass-spec protein most reproducibly stratifies survival.