NUDCD1

Across TCGA cell cohorts, NUDCD1 mutation is significantly associated with the RNA expression of many other genes, with 520 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NUDCD1-associated genes across cancer lineages are SKOR2, PRAMEF4, and CBY1. Each is linked with NUDCD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUDCD1-to-partner and partner-to-NUDCD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SKOR2 grouped by NUDCD1-low versus NUDCD1-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUDCD1→partner) and Y-score (partner→NUDCD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SKOR2 →	+0.017	+4.285	<.001	.007	3	1
STOMACH	PRAMEF4 →	+0.005	+4.285	<.001	.007	3	1
LARGE_INTESTINE	CBY1 →	+0.579	+3.299	.004	.004	3	1
LARGE_INTESTINE	SAMM50 →	+0.529	+3.064	.004	.009	3	1
LARGE_INTESTINE	RBFA →	+0.818	+3.212	.001	.006	3	1
LARGE_INTESTINE	USP14 →	+0.701	+3.299	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 520 associations by consensus.

SKOR2 by NUDCD1 expression — STOMACH

Explore this box plot interactively →