NUDC

Across TCGA pan-cancer cohorts, NUDC mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NUDC data layer compared with 27 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NUDC mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NUDC expression acts as an unfavorable survival marker, although some lineages such as UCEC show a favorable association.

CCRCC, UCEC, and HNSC are the cancer types where NUDC mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Tertile	All	0.699	0.929	.004	26	view →
UCEC	DFS	Median	All	0.960	0.851	.029	10	view →
HNSC	DFS	Median	All	0.687	0.850	.016	8	view →
PDAC	OS	Tertile	All	0.304	0.507	.047	2	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NUDC–CCRCC (OS)

Open the CCRCC breakdown →