NUCKS1P1

Across TCGA patient cohorts, NUCKS1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,128 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NUCKS1P1-associated GO terms across cancer lineages are Regulation of microtubule cytoskeleton organization, Regulation of mRNA catabolic process, and Protein K48-linked ubiquitination. Each is linked with NUCKS1P1 in more than 11 cancer types. Because this analysis shows association rather than direction, both NUCKS1P1-to-partner and partner-to-NUCKS1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of microtubule cytoskeleton organization grouped by NUCKS1P1-low versus NUCKS1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUCKS1P1→partner) and Y-score (partner→NUCKS1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of microtubule cytoskeleton organization →	+0.038	+0.119	<.001	<.001	3	12
STAD	Regulation of mRNA catabolic process →	+0.040	+0.135	<.001	<.001	3	12
STAD	Protein K48-linked ubiquitination →	+0.048	+0.141	<.001	<.001	3	11
STAD	Cellular response to ionizing radiation →	+0.047	+0.146	<.001	<.001	3	11
ESCA	Positive regulation of mRNA processing →	+0.052	+0.147	<.001	<.001	3	11
STAD	Negative regulation of DNA metabolic process →	+0.033	+0.128	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,128 associations by consensus.

Regulation of microtubule cytoskeleton organization by NUCKS1P1 expression — STAD

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