NUCB1

Across TCGA patient cohorts, NUCB1 RNA expression is significantly associated with the protein abundance of many other proteins, with 9,898 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUCB1-associated proteins across cancer lineages are P3H3, PARP4, and PARP4_T101. Each is linked with NUCB1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NUCB1-to-partner and partner-to-NUCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUCB1 versus P3H3 in OV, with a Pearson correlation of 0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NUCB1→partner) and Y-score (partner→NUCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	P3H3 →	+0.601	+0.570	.003	.004	3	4
GBM	PARP4 →	+0.413	+0.256	.001	.008	3	4
GBM	PARP4_T101 →	+0.464	+0.314	.001	.001	3	4
OV	PLS3 →	+0.569	+0.431	<.001	.001	3	4
OV	BAX →	+0.243	+0.555	<.001	<.001	3	4
OV	CRTAP →	+0.727	+0.769	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,898 associations by consensus.

NUCB1 vs P3H3 — OV

Explore this scatter interactively →