NUCB1

Across TCGA patient cohorts, NUCB1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,957 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NUCB1-associated genes across cancer lineages are CD63, KIF26B, and PSAT1. Each is linked with NUCB1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NUCB1-to-partner and partner-to-NUCB1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NUCB1 versus CD63 in GBM, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUCB1→partner) and Y-score (partner→NUCB1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CD63 →	+0.735	+0.342	<.001	<.001	3	5
UCEC	KIF26B →	+1.031	+0.289	.003	.001	3	5
LSCC	PSAT1 →	-1.244	-0.281	<.001	<.001	3	5
BRCA	KCNE4 →	+1.561	+0.254	.007	.002	3	5
GBM	COL6A3 →	+1.611	+0.291	<.001	<.001	3	5
GBM	COL1A2 →	+1.515	+0.271	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,957 associations by consensus.

NUCB1 vs CD63 — GBM

Explore this scatter interactively →