NUBPL

Across TCGA pan-cancer cohorts, NUBPL mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NUBPL data layer compared with 20 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NUBPL mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NUBPL expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, LUAD, and PDAC are the cancer types where NUBPL mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Tertile	All	1.000	0.883	.013	66	view →
LUAD	DFS	Quartile	III,IV	0.781	0.215	.006	17	view →
PDAC	DFS	Median	All	0.840	0.686	.002	11	view →
HNSC	OS	Median	II,III,IV	0.608	0.816	.012	5	view →
GBM	OS	Tertile	All	0.907	0.749	.004	4	view →
LSCC	DFS	Tertile	All	0.701	1.000	.049	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NUBPL–COAD (DFS)

Open the COAD breakdown →