NUBP2

Across TCGA patient cohorts, NUBP2 mutation is significantly associated with the total protein of many other genes, with 10 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NUBP2-associated genes across cancer lineages are EGFR_pY1068, JNK2, and NF2. Each is linked with NUBP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NUBP2-to-partner and partner-to-NUBP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, EGFR_pY1068 grouped by NUBP2-low versus NUBP2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NUBP2→partner) and Y-score (partner→NUBP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.252	-3.459	.046	.005	3	1
UCEC	JNK2 →	+0.265	+3.009	.007	.019	3	1
UCEC	NF2 →	+0.275	+2.321	.011	.035	3	1
UCEC	Annexin-1 →	+0.526	+2.827	.047	.035	3	1
UCEC	Shc_pY317 →	-0.191	-3.000	.012	.036	3	1
UCEC	4E-BP1_pS65 →	+0.214	+2.335	.029	.020	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

EGFR_pY1068 by NUBP2 expression — UCEC

Explore this box plot interactively →