NUBP1

Across TCGA pan-cancer cohorts, NUBP1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated NUBP1 data layer compared with 19 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NUBP1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NUBP1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, COAD, and CCRCC are the cancer types where NUBP1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.594	0.267	<.001	20	view →
COAD	DFS	Tertile	II,III,IV	0.887	1.000	.017	12	view →
CCRCC	OS	Median	All	0.756	0.935	.006	8	view →
LSCC	OS	Tertile	II,III,IV	0.532	0.815	.023	7	view →
HNSC	OS	Median	All	1.000	0.497	.046	4	view →
LUAD	DFS	Quartile	III,IV	0.627	0.911	.044	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NUBP1–PDAC (DFS)

Open the PDAC breakdown →