NUBP1

Across TCGA cell cohorts, NUBP1 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,752 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NUBP1-associated GO terms across cancer lineages are Regulation of sister chromatid segregation, Regulation of chromosome segregation, and Spindle elongation. Each is linked with NUBP1 in more than 10 cancer types. Because this analysis shows association rather than direction, both NUBP1-to-partner and partner-to-NUBP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of sister chromatid segregation grouped by NUBP1-low versus NUBP1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NUBP1→partner) and Y-score (partner→NUBP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Regulation of sister chromatid segregation →	+0.085	+0.603	.004	<.001	3	11
KIDNEY	Regulation of chromosome segregation →	+0.084	+0.571	.005	.001	3	11
KIDNEY	Spindle elongation →	+0.166	+0.354	.002	.007	3	10
KIDNEY	DNA replication initiation →	+0.146	+0.521	<.001	.002	3	9
BREAST	DNA replication-dependent chromatin assembly →	+0.128	+0.835	<.001	<.001	3	9
KIDNEY	Double-strand break repair via break-induced replication →	+0.186	+0.585	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,752 associations by consensus.

Regulation of sister chromatid segregation by NUBP1 expression — KIDNEY

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