NUB1

Across TCGA pan-cancer cohorts, NUB1 mass-spec protein is linked to patient survival in 8 of 34 cancer types, making it a survival-associated NUB1 data layer compared with 24 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NUB1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NUB1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and UCEC show a favorable association.

COAD, PDAC, and CCRCC are the cancer types where NUB1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.906	1.000	.008	84	view →
PDAC	DFS	Quartile	All	0.915	0.652	.001	30	view →
CCRCC	OS	Median	All	0.818	0.980	.004	28	view →
UCEC	DFS	Median	All	0.965	0.845	.006	12	view →
LSCC	OS	Tertile	II,III,IV	0.746	0.964	.011	9	view →
LUAD	DFS	Median	III,IV	0.696	0.351	.014	7	view →
GBM	DFS	Median	All	0.670	0.818	.031	1	view →
HNSC	DFS	Median	IV	1.000	0.924	.037	1	view →

Pink = unfavorable, green = favorable. Showing the 8 strongest of 8 lineages.

NUB1–COAD (DFS)

Open the COAD breakdown →