NTSR1

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NTSR1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NTSR1 data layer compared with 25 for mass-spec protein and 5 for mutation status.

The strongest signal is observed in glioblastoma multiforme (GBM), where higher NTSR1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NTSR1 expression acts as an unfavorable survival marker.

GBM, LSCC, and LUAD are the cancer types where NTSR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
GBMDFSMedianAll0.2050.379.00214view →
LSCCOSMedianAll0.8981.000.01011view →
LUADOSMedianIII,IV0.6511.000.0223view →
HNSCDFSMedianAll0.5780.868.0311view →
Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NTSR1–GBM (DFS)

Kaplan–Meier survival curve for NTSR1 mass-spec protein-high vs -low samples in GBM.

Open the GBM breakdown →

Exploration