NTS

Across TCGA cell cohorts, NTS RNA expression is significantly associated with the go_rna of many other GO terms, with 1,614 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NTS-associated GO terms across cancer lineages are Tetrapyrrole biosynthetic process, Porphyrin-containing compound biosynthetic process, and Cardiolipin acyl-chain remodeling. Each is linked with NTS in more than 8 cancer types. Because this analysis shows association rather than direction, both NTS-to-partner and partner-to-NTS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Tetrapyrrole biosynthetic process grouped by NTS-low versus NTS-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NTS→partner) and Y-score (partner→NTS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUSC	Tetrapyrrole biosynthetic process →	+0.125	+2.724	<.001	.007	3	9
LUNG_NSCLC_LUSC	Porphyrin-containing compound biosynthetic process →	+0.125	+2.724	<.001	.007	3	9
BLOOD_Leukemia	Cardiolipin acyl-chain remodeling →	+0.088	+1.016	<.001	.003	3	6
STOMACH	DNA-templated transcription initiation →	+0.067	+1.106	<.001	.002	3	6
LUNG_NSCLC_LUAD	Regulation of proteolysis →	-0.050	-1.945	.006	.007	3	6
LIVER	Regulation of potassium ion import →	-0.162	-4.024	.006	.004	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,614 associations by consensus.

Tetrapyrrole biosynthetic process by NTS expression — LUNG_NSCLC_LUSC

Explore this box plot interactively →