NTRK3-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NTRK3-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated NTRK3-AS1 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher NTRK3-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NTRK3-AS1 expression acts as an unfavorable survival marker, although some lineages such as LGG and THCA show a favorable association.

ACC, KIRC, and LAML are the cancer types where NTRK3-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
ACCOSTertileAll0.2780.845<.00148view →
KIRCOSTertileII,III,IV0.4060.581.01035view →
LAMLDFSTertileAll0.3560.610.02424view →
LIHCOSTertileII,III,IV0.0420.772<.00118view →
KIRPOSTertileAll0.4600.758.01412view →
LUSCOSTertileIII,IV0.2160.669.0379view →
LGGOSTertileAll0.9240.847.0098view →
DLBCOSQuartileII,III,IV0.6401.000.0265view →
THCADFSMedianII,III,IV0.9760.895.0335view →
TGCTDFSQuartileAll0.3200.688.0174view →
PCPGOSTertileAll0.9040.990.0144view →
THYMDFSTertileII,III,IV1.0000.627.0393view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

NTRK3-AS1–ACC (OS)

Kaplan–Meier survival curve for NTRK3-AS1 RNA-high vs -low samples in ACC.

Open the ACC breakdown →

Exploration