Across TCGA patient cohorts, NTRK1 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,846 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NTRK1-associated proteins across cancer lineages are WIPF1, DOCK2, and DOK2. Each is linked with NTRK1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NTRK1-to-partner and partner-to-NTRK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NTRK1→partner) and Y-score (partner→NTRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	WIPF1 →	+0.326	+0.427	.001	<.001	3	8
GBM	DOCK2 →	+0.455	+0.474	<.001	<.001	3	7
GBM	DOK2 →	+0.812	+0.730	<.001	<.001	3	7
GBM	GRAP2 →	+0.568	+0.697	.004	<.001	3	7
BRCA	PLEKHO2 →	+0.384	+0.287	<.001	<.001	3	7
GBM	TBC1D2B →	+0.406	+0.581	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,846 associations by consensus.

Exploration

NTRK1 survival (RNA) · tumor vs normal (RNA) · all NTRK1 data types