Across TCGA cell cohorts, NTRK1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,648 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NTRK1-associated GO terms across cancer lineages are Regulation of heart rate by cardiac conduction, Cardiac conduction, and DNA-templated transcription initiation. Each is linked with NTRK1 in more than 8 cancer types. Because this analysis shows association rather than direction, both NTRK1-to-partner and partner-to-NTRK1 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NTRK1→partner) and Y-score (partner→NTRK1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Regulation of heart rate by cardiac conduction →	-0.158	-0.328	<.001	.003	3	9
OESOPHAGUS	Cardiac conduction →	-0.131	-0.334	.003	.006	3	8
UPPER_AERODIGESTIVE_TRACT	DNA-templated transcription initiation →	+0.068	+0.063	.002	.002	2	9
BONE	Transcription initiation at RNA polymerase II promoter →	+0.072	+1.009	<.001	<.001	3	8
BLOOD_Myeloma	tRNA transcription by RNA polymerase III →	+0.064	+0.295	<.001	.004	3	8
BONE	Protein-DNA complex organization →	+0.064	+1.006	.009	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,648 associations by consensus.

Exploration

NTRK1 survival (RNA) · tumor vs normal (RNA) · all NTRK1 data types