Across TCGA pan-cancer cohorts, NTPCR mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NTPCR data layer compared with 24 for mass-spec protein and 2 for mutation status.
The strongest signal is observed in colon adenocarcinoma (COAD), where higher NTPCR mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NTPCR expression acts as an unfavorable survival marker, although some lineages such as COAD and LSCC show a favorable association.
COAD, LSCC, and CCRCC are the cancer types where NTPCR mass-spec protein most reproducibly stratifies survival.