NTNG1

Across TCGA patient cohorts, NTNG1 mutation is significantly associated with the RNA expression of many other genes, with 4,777 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NTNG1-associated genes across cancer lineages are CORO2B, TSPY26P, and FMO4. Each is linked with NTNG1 in more than 3 cancer types. Because this analysis shows association rather than direction, both NTNG1-to-partner and partner-to-NTNG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CORO2B grouped by NTNG1-low versus NTNG1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTNG1→partner) and Y-score (partner→NTNG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CORO2B →	-1.615	-2.150	<.001	.003	3	4
STAD	TSPY26P →	-0.750	-3.087	.001	<.001	3	4
STAD	FMO4 →	-0.571	-2.662	<.001	.005	3	4
LUAD	EBF4 →	-0.832	-2.789	<.001	.003	3	4
LIHC	CICP15 →	+0.018	+5.355	<.001	.005	3	3
COAD	HK2 →	+0.577	+3.361	.003	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,777 associations by consensus.

CORO2B by NTNG1 expression — SKCM

Explore this box plot interactively →