NTNG1

Across TCGA cell cohorts, NTNG1 mutation is significantly associated with the RNA expression of many other genes, with 209 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NTNG1-associated genes across cancer lineages are OR12D1, KCNK16, and ODF1. Each is linked with NTNG1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTNG1-to-partner and partner-to-NTNG1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR12D1 grouped by NTNG1-low versus NTNG1-high in LUNG_NSCLC_LUAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTNG1→partner) and Y-score (partner→NTNG1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	OR12D1 →	+0.019	+3.472	<.001	.004	3	2
LUNG_NSCLC_LUAD	KCNK16 →	+0.016	+3.189	.003	.007	3	2
SKIN	ODF1 →	+0.013	+4.022	<.001	.006	3	1
SKIN	PDCL2 →	+0.323	+3.345	<.001	.007	3	1
SKIN	OR2T1 →	+0.006	+4.022	<.001	.006	3	1
SKIN	TPPP2 →	+0.056	+3.632	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 209 associations by consensus.

OR12D1 by NTNG1 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →