NTN4

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NTN4 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,107 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NTN4-associated GO terms across cancer lineages are Membrane raft assembly, Cell-substrate adhesion, and Regulation of calcium ion transport into cytosol. Each is linked with NTN4 in more than 14 cancer types. Because this analysis shows association rather than direction, both NTN4-to-partner and partner-to-NTN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane raft assembly grouped by NTN4-low versus NTN4-high in LUNG_NSCLC_LUSC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN4→partner) and Y-score (partner→NTN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUSCMembrane raft assembly →+0.252+3.672.001<.001315
BONECell-substrate adhesion →+0.180+2.818<.001<.001314
SOFT_TISSUERegulation of calcium ion transport into cytosol →+0.224+2.046<.001<.001314
BONESubstrate adhesion-dependent cell spreading →+0.225+3.136<.001<.001314
SOFT_TISSUERegulation of proteolysis →+0.124+2.937<.001<.001313
BONEWound healing →+0.136+2.284<.001.001313
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,107 associations by consensus.

Membrane raft assembly by NTN4 expression — LUNG_NSCLC_LUSC

Box plot of Membrane raft assembly in NTN4-low vs NTN4-high samples in LUNG_NSCLC_LUSC.

Explore this box plot interactively →

Exploration