NTN4

Across TCGA cell cohorts, NTN4 mutation is significantly associated with the RNA expression of many other genes, with 2 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible NTN4-associated genes across cancer lineages are SIGLEC8 and ELOA3DP. Each is linked with NTN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTN4-to-partner and partner-to-NTN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SIGLEC8 grouped by NTN4-low versus NTN4-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTN4→partner) and Y-score (partner→NTN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	SIGLEC8 →	+0.006	+5.285	<.001	.003	3	1
LARGE_INTESTINE	ELOA3DP →	+0.035	+4.688	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

SIGLEC8 by NTN4 expression — STOMACH

Explore this box plot interactively →