NTM

Across TCGA patient cohorts, NTM protein abundance is significantly associated with the RNA expression of many other genes, with 9,746 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NTM-associated genes across cancer lineages are LMOD1, IRAG1, and SYNDIG1. Each is linked with NTM in more than 7 cancer types. Because this analysis shows association rather than direction, both NTM-to-partner and partner-to-NTM results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NTM versus LMOD1 in CCRCC, with a Pearson correlation of 0.60.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTM→partner) and Y-score (partner→NTM) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	LMOD1 →	+2.089	+1.198	.003	.003	3	7
CCRCC	IRAG1 →	+1.262	+0.998	.005	.004	3	7
OV	SYNDIG1 →	+3.903	+1.673	.001	.009	1	8
CCRCC	SGIP1 →	+1.222	+1.242	.007	.002	2	7
COAD	TGFB3 →	+1.144	+0.553	<.001	<.001	3	6
CCRCC	GLT8D2 →	+0.964	+1.116	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 9,746 associations by consensus.

NTM vs LMOD1 — CCRCC

Explore this scatter interactively →