NTHL1

Across TCGA patient cohorts, NTHL1 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,745 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NTHL1-associated proteins across cancer lineages are DCTPP1, JPT2, and FLYWCH2_S21. Each is linked with NTHL1 in more than 7 cancer types. Because this analysis shows association rather than direction, both NTHL1-to-partner and partner-to-NTHL1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NTHL1 versus DCTPP1 in BRCA, with a Pearson correlation of 0.30.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NTHL1→partner) and Y-score (partner→NTHL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	DCTPP1 →	+0.619	+0.902	<.001	.001	3	8
BRCA	JPT2 →	+0.340	+0.562	<.001	.007	3	7
HNSC	FLYWCH2_S21 →	+0.518	+0.646	<.001	.003	3	7
GBM	NASP →	+0.400	+0.261	<.001	.001	3	5
UCEC	RAB43 →	-0.303	-0.995	<.001	<.001	3	5
LSCC	WBP11 →	+0.248	+0.495	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,745 associations by consensus.

NTHL1 vs DCTPP1 — BRCA

Explore this scatter interactively →