Across TCGA pan-cancer cohorts, NTF3 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of NTF3’s most consistent transcriptional readouts.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where NTF3 RNA is repressed in tumor relative to normal tissue. In most cancer types NTF3 is over-expressed in tumor, although a few such as BLCA and KICH show the opposite, repressed pattern.

BLCA, KICH, and KIRP are the cancer types where NTF3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NTF3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BLCA	Male	All	−2.097	<.001	11	view →
KICH	Male	All	−1.405	<.001	11	view →
KIRP	All	II,III,IV	−1.161	<.001	11	view →
HNSC	Male	II,III,IV	−0.842	<.001	10	view →
LIHC	Female	II,III,IV	−1.719	<.001	9	view →
BRCA	Female	All	−1.002	<.001	6	view →
UCEC	All	All	−0.842	.001	6	view →
CHOL	All	All	−1.660	<.001	5	view →
THCA	All	IV	−0.545	<.001	5	view →
KIRC	Male	All	−0.288	.016	5	view →
COAD	Female	III,IV	−0.516	.002	4	view →
STAD	All	III,IV	−0.496	.005	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

Exploration

Same gene, other analysis: NTF3 RNA expression & survival · all NTF3 data types