NTAN1

Across TCGA pan-cancer cohorts, NTAN1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NTAN1 data layer compared with 26 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher NTAN1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated NTAN1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

COAD, PDAC, and LUAD are the cancer types where NTAN1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	0.867	1.000	.029	12	view →
PDAC	OS	Median	II,III,IV	0.247	0.509	.005	4	view →
LUAD	DFS	Median	All	0.890	0.509	.020	3	view →
GBM	DFS	Tertile	All	0.256	0.439	.039	2	view →
LSCC	OS	Quartile	All	0.777	1.000	.033	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NTAN1–COAD (DFS)

Open the COAD breakdown →