NTAN1

Across TCGA cell cohorts, NTAN1 mutation is significantly associated with the RNA expression of many other genes, with 25 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NTAN1-associated genes across cancer lineages are LCN1, OR5P3, and FAM9A. Each is linked with NTAN1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NTAN1-to-partner and partner-to-NTAN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCN1 grouped by NTAN1-low versus NTAN1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NTAN1→partner) and Y-score (partner→NTAN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	LCN1 →	+0.037	+4.922	<.001	.009	3	1
BLOOD_Leukemia	OR5P3 →	+0.125	+5.201	<.001	.006	3	1
BLOOD_Leukemia	FAM9A →	+0.019	+5.539	<.001	.003	3	1
BLOOD_Leukemia	IZUMO3 →	+0.073	+5.969	<.001	.001	3	1
LARGE_INTESTINE	GALR3 →	+0.085	+3.865	.006	.001	3	1
LARGE_INTESTINE	NCAN →	+0.166	+3.629	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 25 associations by consensus.

LCN1 by NTAN1 expression — BLOOD_Leukemia

Explore this box plot interactively →