Across TCGA pan-cancer cohorts, NT5M Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NT5M data layer compared with 24 for mass-spec protein and 1 for mass-spec protein.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NT5M Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NT5M expression acts as an unfavorable survival marker.

KIRC, HNSC, and SKCM are the cancer types where NT5M Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.152	0.865	<.001	12	view →
HNSC	OS	Median	IV	0.118	0.733	<.001	12	view →
SKCM	OS	Median	All	0.245	0.781	.008	9	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

Exploration

Same gene, other analysis: NT5M tumor-vs-normal RNA expression · all NT5M data types